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New Parkinsons Research


Parkinson’s disease affects about 10 million people worldwide, and usually takes hold when certain types of neurons in the brain become impaired or die off completely. The neurons in question produce a substance called dopamine, which is crucial for enabling the brain to produce smooth and coordinated physical movements.

In new research scientists have delayed the onset of some effects of Parkinson’s in mice by flushing senescent cells from the brain. Six-month-old mice were exposed to paraquat, which caused problems with movement and the development of senescent cells in the brain. The mice where then injected with a drug that destroys these cells, which was found to keep their movement problems at bay.

“The approach may have benefits far beyond Parkinson’s, with other neurodegenerative diseases – and the ageing process more broadly – all being linked to the ill effects of these “senescent” cells, which linger in tissues after entering a state of suspended animation in the body.”

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