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Mouse Vocalizations Provide Insight into Autism


A new technique to study ultrasound vocalizations made by laboratory mice could help further the understanding how genes that affect vocal communication relate to developmental disorders like autism.

Like humans, mice use vocalizations to communicate with each other. Unlike humans, most of that vocalization is conducted in an ultrasonic range, outside the human range of hearing. This makes it difficult to analyse these vocalizations.

“Mice provide a powerful model for understanding the genetic and environmental basis of complex behaviours that often are disrupted in psychiatric disorders and neurodevelopmental disorders, including autism spectrum disorders.”

Each vocalization is time and date stamped, which allows researchers to correlate vocalizations with recorded behavioural interactions. This will be helpful when studying mouse models of developmental disorders.

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