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Permanent Positions

Formulation & Protein Analytics Team Leader
Cambridge , East Anglia

Formulation & Protein Analytics Team Leader
We have an outstanding opportunity in our Antibody Discovery Section for an experienced and dynamic scientist to lead the Formulation and Protein Analytics Team. The focus of this recently formed team is the biophysical assessment and analysis of lead molecules, the use of label-free protein interaction technology supporting early discovery and development and lead candidate formulation and stability testing. We aim to build an industry leading team that delivers high-quality data packages that seamlessly support the CMC manufacture of our advancing drug pipeline.

Key Responsibilities:
 Generation and delivery of high quality and well-documented data packages for advancing the client’s drug candidates that support the CMC manufacture and regulatory submissions
 Stability and biophysical assessment of drug candidates with industry-standard readouts and associated documentation for both discovery and pre-CMC candidates
 Managing of the label-free in-house expert team involving the latest BLI and SPR technology to support discovery and development
 Line managerial responsibility for the team
 Presentation of key findings and provided solutions to project teams, development team and discovery
 Support on-going lab-based work as required

Key Requirements:
 PhD or equivalent with significant employment experience in the relevant area
 In-depth and demonstrated experience in antibody-drug based formulation and analytics
 Extensive technical expertise of protein biophysical characterization procedures and techniques (not limited to) including, DLS, SLS, DSC and DSF and expertise in HPLC method development
 A strong knowledge of excipient and buffer systems designed to maximise antibody stability
 Understanding of the industry-standard data packages required to support CMC and regulatory processes
 Expert knowledge and internal and external recognition of expertise in the area of protein/antibody formulation and analytics

How to apply
To proceed with your application for this role, simply apply to this advert, or alternatively you can send your most recent up to date CV to

Please note, only successful candidates will be contacted. All successful applications are subject to S3 Science’s stringent vetting and security checks.

S3 Science is proud to be an equal opportunities employer and is committed to creating a diverse environment. All qualified applicants will receive consideration for employment without regard to race, colour, religion, gender identity or expression, sexual orientation, national origin, genetics, disability, age or veteran status.

Salary: Competitive
Date Posted: 09/08/2017
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