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In a new study, researchers have found that a bacterium largely responsible for gum disease also contributes to the development of Alzheimer’s disease.

Gum disease is a widespread problem that can lead to more negative outcomes, from tooth loss to an increased risk of cancer.

Now, emerging evidence suggests that one of the bacteria involved in periodontitis could also contribute to the accumulation of toxic proteins in the brain, which scientists have associated with the development of Alzheimer’s disease.

The researchers zeroed in on one bacterium — Porphyromonas gingivalis — which is a Gram-negative oral anaerobe that drives the development of gum disease.

P. gingivalis, the researchers note, also appears in the brains of people who doctors have diagnosed with Alzheimer’s disease, which left the investigators intrigued.

When looking at a mouse model, the team found that infection with P. gingivalis led to greater production of beta-amyloid in the rodents’ brains.

Beta-amyloid is a marker of Alzheimer’s disease in the brain; in this neurodegenerative condition, the toxic protein accumulates in excess, forming into plaques that disrupt normal communication between brain cells.

For the full story follow the link below

How gum disease could lead to Alzheimer’s

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