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New approach to preventing seizures proves effective in mice

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For many people who suffer from neurological disorders, such as epilepsy, there are no viable treatment options. Scientist have developed an implantable device that may one day offer relief. They have shown that the implant can treat problems in the brain, such as epileptic seizures, by delivering brain chemicals – known as neurotransmitters – directly to the cells in the brain that cause the problem.

The implant works by using an electric field to push neurotransmitters out of the device from an internal reservoir. This process, known as electrophoresis, allows for precise control over the dose and timing of drug delivery, which is important for addressing intermittent disorders such as epilepsy.

This is very exciting because this is the first time anyone has seen that an electrophoretic drug delivery device can stop or prevent seizure-like activity. Also, we can see this as a platform technology that could be adapted to help treat many different neurological disorders including epilepsy, Parkinson’s disease and brain tumours.





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