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Permanent Positions

Senior Scientist
London, London

Responsibilities:

You will utilise your expertise to design protein engineering strategies and source new technologies. You’ll work closely with the other research and development teams to optimise protocols and deliver our company-wide milestones.

  • Advance protein expression, purification, characterisation, and analysis capabilities
  • Create assays for high-throughput screening
  • Source, evaluate and test growth factors using high-throughput methodologies
  • Evaluate technologies for the supplementation and cost reduction of proteins in the media
  • Design, plan, and perform complex experiments to ensure deliverables are successfully met within project timelines
  • Determine the most appropriate methodologies to test hypotheses, and identify suitable alternatives if technical problems arise
  • Document research findings clearly in an electronic lab book
  • Write and further develop experimental protocols and generate laboratory SOPs
  • Support the preparation of laboratory risk assessments and maintenance of health and safety protocols
  • Lead and develop the team by providing guidance and support
  • Participate as a key member of the R&D management team with responsibility for day-to-day decision making within your team
  • Provide written and verbal progress reports to the Senior Leadership Team and to external collaborators
  • Keep up to date with field developments and apply these to improve experimental design and assay performance

Qualifications & Experience:

  • A PhD in a relevant area of Biochemistry, Molecular Biology, or a similar field
  • 6 or more years of post-doctoral or industry experience in a relevant area

Essential Experience:

  • Experience in producing, purifying proteins, and analysing their quality and bioactivity
  • Analytical techniques and computational approaches to protein engineering
  • Experience with assay development, high-throughput screening and protein characterization
  • Strong background in cellular and molecular biology technical processes such as: cell-based activity assays, enzyme-based metabolism assays, immunosorbent assays, protein quantification and protein refolding
  • History of refining protocols and methodologies to reduce cost base
  • Skilled at the design, set-up and running of complex experiments
  • Proficient in the detailed statistical analysis and presentation of intricate data sets
  • Experience of writing SOPs and risk assessments under quality management system
  • Organised, self-motivated, and capable of working independently and collaboratively, in a fast-paced team environment
  • Skilled in root cause analysis
  • Management experience with a track record of success delivering R&D projects
  • History of independent investigations and innovative thinking

Desirable

  • Experience in cell culture, with maintenance and differentiation of stem or primary cell types
  • Experience with the development and implementation of automation to support high-throughput assay development approaches
  • Experience in statistical experimental methodologies, design of experiments. Knowledge of analysis packages such as Design Expert
Salary: £35,00 - £45,00 p/a
Date Posted: 24/09/2021
  • S3Science is an equal opportunities employer: our recruitment process is fair, objective and open.

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